As the economy struggles on earth, some companies are setting their views on more space opportunities.
More than 100 companies that make products or offer services ranging from communications satellites to rocket-powered vehicles capable of sending ordinary people into space gathered at Boston's Hynes Convention Center for the seventh Space Investment Summit.
The summit aims to educate entrepreneurs on how to attract seed and early-stage investment money, while letting investors know about space-related business opportunities.
Ventures being discussed included the potential to monitor polar icecaps from space, generate energy off-earth, mine asteroids and use microgravity to develop new drugs for biotechnology and pharmaceutical companies.
"There are plenty of opportunities to do some really good science up there," said Michael Leventhal, an attorney and business consultant.
There is potential for a huge and profitable market for space businesses, but many come with large startup costs. Some speakers said the ventures may need to be funded initially through partnerships with the government.
Right now, the most well-known space-related ventures are flight vehicles that will take tourists into space. Virgin Group Chief Richard Branson and Amazon.com founder Jeff Bezos have invested their own capital in space tourism.
But even those ventures have been hurt by the recession.
In July, Branson signed a deal to sell about a third of his space travel startup Virgin Galactic to a Mideast investment fund, giving the venture an influx of cash. Virgin Group has pumped more than $100 million into its space flight venture since 2004 and hopes to begin commercial flights within two years.
Paul Eckert, an international and commercial strategist with Boeing Co., a sponsor of the summit, said commercial opportunities in space go well beyond space tourism.
"We're talking about space-related business deals, entrepreneurial ventures, any kind of connection with space, not just in space, but involving space — it could be spacesuits, components that might fit into antennae, anything that involves space," Eckert said.
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Friday, October 16, 2009
Nuclear Weapons
A nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission or a combination of fission and fusion. Both reactions release vast quantities of energy from relatively small amounts of matter; a modern thermonuclear weapon weighing little more than a thousand kilograms can produce an explosion comparable to the detonation of more than a billion kilograms of conventional high explosive.
Thus, even single small nuclear devices no larger than traditional bombs can devastate an entire city by blast, fire and radiation. Nuclear weapons are considered weapons of mass destruction, and their use and control has been a major focus of international relations policy since their debut.
In the history of warfare, only two nuclear weapons have been detonated offensively, both near the end of World War II. The first was detonated on the morning of 6 August 1945, when the United States dropped a uranium gun-type device code-named "Little Boy" on the Japanese city of Hiroshima. The second was detonated three days later when the United States dropped a plutonium implosion-type device code-named "Fat Man" on the city of Nagasaki, Japan. These bombings resulted in the immediate deaths of around 120,000 people (mostly civilians) from injuries sustained from the explosion and acute radiation sickness, and even more deaths from long-term effects of ionizing radiation. The use of these weapons was and remains controversial.
Since the Hiroshima and Nagasaki bombings, nuclear weapons have been detonated on over two thousand occasions for testing purposes and demonstration purposes. A few states have possessed such weapons or are suspected of seeking them. The only countries known to have detonated nuclear weapons—and that acknowledge possessing such weapons—are (chronologically) the United States, the Soviet Union (succeeded as a nuclear power by Russia), the United Kingdom, France, the People's Republic of China, India, Pakistan, and North Korea. Israel is also widely believed to possess nuclear weapons, though it does not acknowledge having them.
Thus, even single small nuclear devices no larger than traditional bombs can devastate an entire city by blast, fire and radiation. Nuclear weapons are considered weapons of mass destruction, and their use and control has been a major focus of international relations policy since their debut.
In the history of warfare, only two nuclear weapons have been detonated offensively, both near the end of World War II. The first was detonated on the morning of 6 August 1945, when the United States dropped a uranium gun-type device code-named "Little Boy" on the Japanese city of Hiroshima. The second was detonated three days later when the United States dropped a plutonium implosion-type device code-named "Fat Man" on the city of Nagasaki, Japan. These bombings resulted in the immediate deaths of around 120,000 people (mostly civilians) from injuries sustained from the explosion and acute radiation sickness, and even more deaths from long-term effects of ionizing radiation. The use of these weapons was and remains controversial.
Since the Hiroshima and Nagasaki bombings, nuclear weapons have been detonated on over two thousand occasions for testing purposes and demonstration purposes. A few states have possessed such weapons or are suspected of seeking them. The only countries known to have detonated nuclear weapons—and that acknowledge possessing such weapons—are (chronologically) the United States, the Soviet Union (succeeded as a nuclear power by Russia), the United Kingdom, France, the People's Republic of China, India, Pakistan, and North Korea. Israel is also widely believed to possess nuclear weapons, though it does not acknowledge having them.
Wednesday, October 7, 2009
Experimental and proposed treatments of AIDS
It has been postulated that only a vaccine can halt the pandemic because a vaccine would possibly cost less, thus being affordable for developing countries, and would not require daily treatments. However, even after almost 30 years of research, HIV-1 remains a difficult target for a vaccine.
Research to improve current treatments includes decreasing side effects of current drugs, further simplifying drug regimens to improve adherence, and determining the best sequence of regimens to manage drug resistance. A number of studies have shown that measures to prevent opportunistic infections can be beneficial when treating patients with HIV infection or AIDS. Vaccination against hepatitis A and B is advised for patients who are not infected with these viruses and are at risk of becoming infected.Patients with substantial immunosuppression are also advised to receive prophylactic therapy for Pneumocystis jiroveci pneumonia (PCP), and many patients may benefit from prophylactic therapy for toxoplasmosis and Cryptococcus meningitis as well.
Researchers have discovered an abzyme that can destroy the protein gp120 CD4 binding site. This protein is common to all HIV variants as it is the attachment point for B lymphocytes and subsequent compromising of the immune system.
In Berlin, Germany, a 42-year-old leukemia patient infected with HIV for more than a decade was given an experimental transplant of bone marrow with cells that contained an unusual natural variant of the CCR5 cell-surface receptor. This CCR5-Δ32 variant has been shown to make some cells from people who are born with it resistant to infection with some strains of HIV. Almost two years after the transplant, and even after the patient reportedly stopped taking antiretroviral medications, HIV has not been detected in the patient's blood.
Research to improve current treatments includes decreasing side effects of current drugs, further simplifying drug regimens to improve adherence, and determining the best sequence of regimens to manage drug resistance. A number of studies have shown that measures to prevent opportunistic infections can be beneficial when treating patients with HIV infection or AIDS. Vaccination against hepatitis A and B is advised for patients who are not infected with these viruses and are at risk of becoming infected.Patients with substantial immunosuppression are also advised to receive prophylactic therapy for Pneumocystis jiroveci pneumonia (PCP), and many patients may benefit from prophylactic therapy for toxoplasmosis and Cryptococcus meningitis as well.
Researchers have discovered an abzyme that can destroy the protein gp120 CD4 binding site. This protein is common to all HIV variants as it is the attachment point for B lymphocytes and subsequent compromising of the immune system.
In Berlin, Germany, a 42-year-old leukemia patient infected with HIV for more than a decade was given an experimental transplant of bone marrow with cells that contained an unusual natural variant of the CCR5 cell-surface receptor. This CCR5-Δ32 variant has been shown to make some cells from people who are born with it resistant to infection with some strains of HIV. Almost two years after the transplant, and even after the patient reportedly stopped taking antiretroviral medications, HIV has not been detected in the patient's blood.
Antiviral therapy-treatment of AIDS
Current treatment for HIV infection consists of highly active antiretroviral therapy, or HAART. This has been highly beneficial to many HIV-infected individuals since its introduction in 1996 when the protease inhibitor-based HAART initially became available. Current optimal HAART options consist of combinations (or "cocktails") consisting of at least three drugs belonging to at least two types, or "classes," of antiretroviral agents. Typical regimens consist of two nucleoside analogue reverse transcriptase inhibitors (NARTIs or NRTIs) plus either a protease inhibitor or a non-nucleoside reverse transcriptase inhibitor (NNRTI). Because HIV disease progression in children is more rapid than in adults, and laboratory parameters are less predictive of risk for disease progression, particularly for young infants, treatment recommendations are more aggressive for children than for adults. In developed countries where HAART is available, doctors assess the viral load, rapidity in CD4 decline, and patient readiness while deciding when to recommend initiating treatment.
Standard goals of HAART include improvement in the patient’s quality of life, reduction in complications, and reduction of HIV viremia below the limit of detection, but it does not cure the patient of HIV nor does it prevent the return, once treatment is stopped, of high blood levels of HIV, often HAART resistant. Moreover, it would take more than the lifetime of an individual to be cleared of HIV infection using HAART. Despite this, many HIV-infected individuals have experienced remarkable improvements in their general health and quality of life, which has led to the plummeting of HIV-associated morbidity and mortality. In the absence of HAART, progression from HIV infection to AIDS occurs at a median of between nine to ten years and the median survival time after developing AIDS is only 9.2 months.HAART is thought to increase survival time by between 4 and 12 years.
For some patients, which can be more than fifty percent of patients, HAART achieves far less than optimal results, due to medication intolerance/side effects, prior ineffective antiretroviral therapy and infection with a drug-resistant strain of HIV. Non-adherence and non-persistence with therapy are the major reasons why some people do not benefit from HAART. The reasons for non-adherence and non-persistence are varied. Major psychosocial issues include poor access to medical care, inadequate social supports, psychiatric disease and drug abuse. HAART regimens can also be complex and thus hard to follow, with large numbers of pills taken frequently. Side effects can also deter people from persisting with HAART, these include lipodystrophy, dyslipidaemia, diarrhoea, insulin resistance, an increase in cardiovascular risks and birth defects. Anti-retroviral drugs are expensive, and the majority of the world's infected individuals do not have access to medications and treatments for HIV and AIDS.
Standard goals of HAART include improvement in the patient’s quality of life, reduction in complications, and reduction of HIV viremia below the limit of detection, but it does not cure the patient of HIV nor does it prevent the return, once treatment is stopped, of high blood levels of HIV, often HAART resistant. Moreover, it would take more than the lifetime of an individual to be cleared of HIV infection using HAART. Despite this, many HIV-infected individuals have experienced remarkable improvements in their general health and quality of life, which has led to the plummeting of HIV-associated morbidity and mortality. In the absence of HAART, progression from HIV infection to AIDS occurs at a median of between nine to ten years and the median survival time after developing AIDS is only 9.2 months.HAART is thought to increase survival time by between 4 and 12 years.
For some patients, which can be more than fifty percent of patients, HAART achieves far less than optimal results, due to medication intolerance/side effects, prior ineffective antiretroviral therapy and infection with a drug-resistant strain of HIV. Non-adherence and non-persistence with therapy are the major reasons why some people do not benefit from HAART. The reasons for non-adherence and non-persistence are varied. Major psychosocial issues include poor access to medical care, inadequate social supports, psychiatric disease and drug abuse. HAART regimens can also be complex and thus hard to follow, with large numbers of pills taken frequently. Side effects can also deter people from persisting with HAART, these include lipodystrophy, dyslipidaemia, diarrhoea, insulin resistance, an increase in cardiovascular risks and birth defects. Anti-retroviral drugs are expensive, and the majority of the world's infected individuals do not have access to medications and treatments for HIV and AIDS.
Insuring Savings With A Simple Checklist
Insurance needs change with age and circumstance, yet few people take the time to review their insurance needs and find savings to fatten their monthly budget. It is, though, one of the easiest ways to cut living expenses and save money. On the bright side, it takes just a phone call to switch policies, get a new quote, or change the terms of an existing policy. Here are a few things to check every year, to determine if you can save money on your insurance bills.
* Get new quotes – Every year, it pays to look around and see what other companies are offering for their insurance policies and costs. Just shopping around can save hundreds.
* Bundle your insurance needs – If you have your car with a company that also offers homeowners insurance, it can save you money on both, typically a 10% discount.
* Check your deductibles – If you can stand to have higher deductibles, it will lower your insurance premium.
* Opt out of term life insurance – Once your kids are no longer dependent on you for support, you can cancel your term life insurance policies. Otherwise, you should carry about seven times your income on term life insurance to take care of your kids in case you die.
* Go with a group – Are you a member of a group that offers special discounts on life insurance? Check them out. Members of the AARP, teachers, student body alumnae, retired, or military personnel all can find group discounts for being a member of any of these groups.
* Remove extras you don't need – If you already have towing benefits with AAA, there's no need to carry towing insurance through another provider too. Collision insurance is only good to carry for cars that are less than 10 years old, otherwise, it's the same as replacing the old car out-of-pocket (about $1000).
* Pay yearly or semi-yearly – You can save another 5 to 10% of the policy simply by paying ahead of time, instead of monthly. A few extra dollars a month to process the loan on a monthly basis may seem like little, but it can add up to 10% by the end of the year.
* Get new quotes – Every year, it pays to look around and see what other companies are offering for their insurance policies and costs. Just shopping around can save hundreds.
* Bundle your insurance needs – If you have your car with a company that also offers homeowners insurance, it can save you money on both, typically a 10% discount.
* Check your deductibles – If you can stand to have higher deductibles, it will lower your insurance premium.
* Opt out of term life insurance – Once your kids are no longer dependent on you for support, you can cancel your term life insurance policies. Otherwise, you should carry about seven times your income on term life insurance to take care of your kids in case you die.
* Go with a group – Are you a member of a group that offers special discounts on life insurance? Check them out. Members of the AARP, teachers, student body alumnae, retired, or military personnel all can find group discounts for being a member of any of these groups.
* Remove extras you don't need – If you already have towing benefits with AAA, there's no need to carry towing insurance through another provider too. Collision insurance is only good to carry for cars that are less than 10 years old, otherwise, it's the same as replacing the old car out-of-pocket (about $1000).
* Pay yearly or semi-yearly – You can save another 5 to 10% of the policy simply by paying ahead of time, instead of monthly. A few extra dollars a month to process the loan on a monthly basis may seem like little, but it can add up to 10% by the end of the year.
Neural Networks Learn Forex Trading Strategies
The latest buzz in the Forex world is neural networks, a term taken from the artificial intelligence community. In technical terms, neural networks are data analysis methods that consist of a large number of processing units that are linked together by weighted probabilities. In more simple terms, neural networks are a model loosely resembling the way that the human brain works and learns. For several decades now, those in the artificial intelligence community have used the neural network model in creating computers that ‘think’ and ‘learn’ based on the outcomes of their actions.
Unlike the traditional data structure, neural networks take in multiple streams of data and output one result. If there’s a way to quantify the data, there’s a way to add it to the factors being considered in making a prediction. They’re often used in Forex market prediction software because the network can be trained to interpret data and draw a conclusion from it.
Before they can be of any use in making Forex predictions, neural networks have to be ‘trained’ to recognize and adjust for patterns that arise between input and output. The training and testing can be time consuming, but is what gives neural networks their ability to predict future outcomes based on past data. The basic idea is that when presented with examples of pairs of input and output data, the network can ‘learn’ the dependencies, and apply those dependencies when presented with new data. From there, the network can compare its own output to see how close to correct the prediction was, and go back and adjust the weight of the various dependencies until it reaches the correct answer.
This requires that the network be trained with two separate data sets – the training and the testing set. One of the strengths of neural networks is that it can continue to learn by comparing its own predictions with the data that is continually fed to it. Neural networks are also very good at combining both technical and fundamental data, thus making a best of both worlds scenario. Their very power allows them to find patterns that may not have been considered, and apply those patterns to prediction to come up with uncannily accurate results.
Unfortunately, this strength can also be a weakness in the use of neural networks for trading predictions. Ultimately, the output is only as good as the input. They are very good at correlating data even when you feed them enormous amounts of it. They are very good at extracting patterns from widely disparate types of information – even when no pattern or relationship exists. Its other major strength – the ability to apply intelligence without emotion – after all, a computer doesn’t have an ego – can also become a weakness when dealing with a volatile market. When an unknown factor is introduced, the artificial neural network has no way of assigning an emotional weight to that factor.
There are currently dozens of Forex trading platforms on the market that incorporate neural network theory and technology to ‘teach’ the network your system and let it make predictions and generate buy/sell orders based on it. The important thing to keep in mind is that the most basic rule of Forex trading applies when you set out to build your neural network – educate yourself and know what you’re doing. Whether you’re dealing with technical analysis, fundamentals, neural networks or your own emotions, the single most important thing you can do to ensure your success in Forex trading is to learn all you can.
Unlike the traditional data structure, neural networks take in multiple streams of data and output one result. If there’s a way to quantify the data, there’s a way to add it to the factors being considered in making a prediction. They’re often used in Forex market prediction software because the network can be trained to interpret data and draw a conclusion from it.
Before they can be of any use in making Forex predictions, neural networks have to be ‘trained’ to recognize and adjust for patterns that arise between input and output. The training and testing can be time consuming, but is what gives neural networks their ability to predict future outcomes based on past data. The basic idea is that when presented with examples of pairs of input and output data, the network can ‘learn’ the dependencies, and apply those dependencies when presented with new data. From there, the network can compare its own output to see how close to correct the prediction was, and go back and adjust the weight of the various dependencies until it reaches the correct answer.
This requires that the network be trained with two separate data sets – the training and the testing set. One of the strengths of neural networks is that it can continue to learn by comparing its own predictions with the data that is continually fed to it. Neural networks are also very good at combining both technical and fundamental data, thus making a best of both worlds scenario. Their very power allows them to find patterns that may not have been considered, and apply those patterns to prediction to come up with uncannily accurate results.
Unfortunately, this strength can also be a weakness in the use of neural networks for trading predictions. Ultimately, the output is only as good as the input. They are very good at correlating data even when you feed them enormous amounts of it. They are very good at extracting patterns from widely disparate types of information – even when no pattern or relationship exists. Its other major strength – the ability to apply intelligence without emotion – after all, a computer doesn’t have an ego – can also become a weakness when dealing with a volatile market. When an unknown factor is introduced, the artificial neural network has no way of assigning an emotional weight to that factor.
There are currently dozens of Forex trading platforms on the market that incorporate neural network theory and technology to ‘teach’ the network your system and let it make predictions and generate buy/sell orders based on it. The important thing to keep in mind is that the most basic rule of Forex trading applies when you set out to build your neural network – educate yourself and know what you’re doing. Whether you’re dealing with technical analysis, fundamentals, neural networks or your own emotions, the single most important thing you can do to ensure your success in Forex trading is to learn all you can.
Forex Software - Choosing The Best
When it comes to forex trading the forex software you choose is essential. There are so many forex trading companies all competing for your business that choosing the right forex software can be quite a difficult task. Most of the forex software products available offers live online forex trading platforms but what other components are vital when it comes to your forex software.
Key Elements For Your Forex Software
Before purchasing any forex software there are a few essential items that should be included. The most important is security and your online forex trading software should include a 128 bit SSL encryption which will prevent hackers from accessing any of your personal details and information such as your account balance, transaction history, etc.
Providing the best security for your forex trading will include a company that provides 24 hour technical server support for your forex software, 24 hour maintenance should anything go wrong, daily backups of all information, and a security system that has been designed to prevent any unauthorized access. Along with these security protocols there are also some forex trading companies that use smart cards and fingerprint scanners to ensure that only their employees can have access to their servers.
Another important factor when it comes to choosing your forex software is to check what the company's downtime is like. When it comes to trading forex and particularly your online forex trading you need to ensure that the forex software you choose is reliable and available 24 hours a day. The forex software you choose for your forex trading should also have technical support available at all times should your session be cut short.Ensuring that all the above features are listed in the forex software you choose will help to ensure your forex trading success.Anyway, a forex software is a must have if you want to earn money.
Key Elements For Your Forex Software
Before purchasing any forex software there are a few essential items that should be included. The most important is security and your online forex trading software should include a 128 bit SSL encryption which will prevent hackers from accessing any of your personal details and information such as your account balance, transaction history, etc.
Providing the best security for your forex trading will include a company that provides 24 hour technical server support for your forex software, 24 hour maintenance should anything go wrong, daily backups of all information, and a security system that has been designed to prevent any unauthorized access. Along with these security protocols there are also some forex trading companies that use smart cards and fingerprint scanners to ensure that only their employees can have access to their servers.
Another important factor when it comes to choosing your forex software is to check what the company's downtime is like. When it comes to trading forex and particularly your online forex trading you need to ensure that the forex software you choose is reliable and available 24 hours a day. The forex software you choose for your forex trading should also have technical support available at all times should your session be cut short.Ensuring that all the above features are listed in the forex software you choose will help to ensure your forex trading success.Anyway, a forex software is a must have if you want to earn money.
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